Response to comment on "Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2".
نویسندگان
چکیده
Vassalli et al.'s study does not involve or provide additional data regarding influenza virus, influenza vaccines, human samples, animal models of narcolepsy, or experiments related to mimicry and cross-reactivity. They present data on the distribution of hypocretin (HCRT) (also known as orexin) receptors in the brain of an engineered mouse developed by them.
منابع مشابه
Mechanistic insights into influenza vaccine-associated narcolepsy
We previously reported an increased frequency of antibodies to hypocretin (HCRT) receptor 2 in sera obtained from narcoleptic patients who received the European AS03-adjuvanted vaccine Pandemrix (GlaxoSmithKline Biologicals, s.a.) for the global influenza A H1N1 pandemic in 2009 [A(H1N1)pdm09]. These antibodies cross-reacted with a particular fragment of influenza nucleoprotein (NP) - one of th...
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عنوان ژورنال:
- Science translational medicine
دوره 7 294 شماره
صفحات -
تاریخ انتشار 2015